He is best known for finishing as runner up on the sixth series of British talent show The X Factor in 2009. In 2011 and 2012, Murs co-hosted The Xtra Factor with Caroline Flack. In 2015, Murs and Flack presented The X Factor after the departure of Dermot O'Leary.
Murs has so far released six studio albums; Olly Murs (2010), In Case You Didn't Know (2011), Right Place Right Time (2012), Never Been Better (2014), 24Hrs (2016) and You Know I Know (2018).
Since 2018, Murs has served as a coach on The Voice UK.